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This response matches the smooth muscle fibre bundle orientation within the tunica muscularis.
The last group likely reflects the mammalian equivalent of tissue polarity/PCP signaling, as defined in Drosophila, and it includes CNS axon guidance, hair follicle and tongue papilla orientation, and inner ear sensory hair bundle orientation.
Therefore, we aimed to determine if automated polarized light microscopy methods of quantifying two structural parameters; fibrin fiber bundle orientation and fibrin's optical retardation (OR: a measure of molecular anisotropy) could be used to assess thrombi.
To compare fibrin fiber bundle orientation we analyzed picrosirius red-stained sections obtained from clots formed: (A) in vitro, (B) in injured and stenotic coronary arteries, and (C) in surgically created aortic aneurysms (n = 6 for each group).
The core idea is to treat such a fibre as a network of CNT bundles, similar to the structure of high-performance polymer fibres, with tensile properties defined by the CNT bundle orientation distribution function (ODF), shear modulus and shear strength.
Other acute remodeling evidence included smooth muscle cell hypertrophy and changes in smooth muscle bundle orientation from the longitudinally biased orientation in the normal bladders to the biphasic (both longitudinal and circumferential) orientation in the SCI bladders [9].
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Hair cells in the macular receptors, the utricle and the saccule, are divided by a central region named striola, in two groups with opposite stereociliary bundle orientations [ 10].
Quantification performed in the medial coil revealed a clear difference in OHC bundle orientations between mutant and control specimens (Fig. 5C).
In the medial coil of the cochlea, OHC diameters were measured at the level below adherens junctions, and stereociliary bundle orientations defined as described in the previous paragraph, using the Image-Pro Plusoftwarere (Media Cybernetics) (n = 76 OHCs, 4 mutant cochleas; n = 21 OHCs, 2 control cochleas).
However, fluorescence microscopy does not provide the necessary resolution to reveal the ultrastructural details of MT bundles, namely the number of MTs per bundle, MT orientation within the bundle, and the inter-MT spacing (the distance from MT wall to MT wall).
The hypothesis was that also in double bundle reconstruction the orientation of femoral tunnel could affect the final knee stability.
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