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The Foster Wheeler Corporation has been awarded a $200 million contract to build a bulk pharmaceuticals plant for the Schering-Plough Corporation in Singapore.
Tyco, a diversified manufacturing and service company based in Bermuda, will add Bard's line of catheters and other products to help treat cancer, prostate disease and incontinence to a Tyco medical unit that includes diagnostic imaging devices and bulk pharmaceuticals.
Max India, which among other activities makes bulk pharmaceuticals, has signed a deal with an affiliate of Harvard Medical School to conduct clinical trials in India and in other developing countries.
Considering its particular advantages in methanol utilization and protein expression, P. pastoris is expected to be developed into a promising microorganism for the synthesis of bulk pharmaceuticals from a potentially renewable and low-cost feedstock, methanol.
TPI's manufacturing capacity for bulk pharmaceuticals prior to the European Commission grant was limited [ 18][ 25][ 27].
Like many Sub-Saharan African and LDC manufacturers, TPI only has limited capability to formulate and package bulk pharmaceuticals, limiting its ability to compete [ 39][ 25][ 27].
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"China is turning into one of the major bulk pharmaceutical producers in the world," she wrote.
Congress has criticized the oversight by the Food and Drug Administration of bulk pharmaceutical ingredients made by foreign manufacturers and sold in the United States.
"The impact of chemical products on the bulk pharmaceutical market hints at a much larger problem: a huge hole in drug safety," the drug agency publication stated.
An adsorptive stripping differential pulse voltammetric method (AdSDPV) was developed for the determination of LIN in bulk, pharmaceutical formulations and urine samples.
Athermal solvent exchange from one organic synthesis step to the next step is highly desirable in bulk pharmaceutical manufacturing due to the thermally labile nature of the active intermediates.
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