Effective therapy, in particular with methotrexate (MTX) and more pronounced with biologicals plus MTX, has abolished the bulk of extra-articular manifestations and amyloidosis, has reduced disease-related comorbidity such as cardiovascular disease and lymphoma, and has essentially normalized life expectancy.
"We think that the bulk of these extra CFCs are coming from things like old fridges.
The bulk of his extra fiscal tightening will come from spending cuts, which will yield 1.8%.
The bulk of their extra time went into leisure and recreation, particularly watching television, socializing and playing sports and games.
The bulk of the extra emissions from LNG are generated by the tankers that bring it to the UK – these and all other shipping emissions remain the responsibility of no one in particular.
They had urged him to keep in place the bulk of the extra 30,000 troops he committed to the "surge" until the end of 2012, so a drawdown can begin in 2013.
Mr Sachs envisages funnelling most of it through national governments, who would have to train many more teachers, engineers, nurses and other professionals, and then persuade the best of them not to emigrate to rich countries.But is it not likely that corrupt elites will snaffle the bulk of the extra money, either directly or by awarding contracts to their cronies?
Stormont sources say the bulk of this extra £1bn consisted of reassigning the Northern Ireland Executive's current borrowing power, known as the Reform and Reinvestment Initiative.
The bulk of the extra intake is coming in on package holidays from Taiwan and Japan – and such price-sensitive travellers are the ones likely to be put off by high permit charges for the main attractions.
The budget proposals indicate that while collections of direct taxes (that is, taxes on personal incomes and corporate profits) would come down, the bulk of the extra revenues the government hopes to garner will come from indirect taxes, notably taxes on a wide range of services.
