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Recent follow-up studies of the CRC EMT-like transcriptome subclass unexpectedly uncovered that the source of mesenchymal gene expression is not the bulk of epithelial tumor cells, but stromal cells such as the cancer-associated fibroblasts within the tumor nodule (Calon et al, 2015; Isella et al, 2015).
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Since canine mammary tumours in bulk are of epithelial origin this kind of cells is subjected to many studies.
Volume of epithelial lining fluid.
The pathway signature showed that ccRCC cells are quite different from normal renal cells, the bulk of which are epithelial cells.
Under other conditions, such as pregnancy, it is probable that ductal and alveolar progenitor cells form the bulk of the increased mammary epithelial cell population [ 7].
Keratin proteins belong to two distinct classes, type I acidic and type II basic and represent the bulk of IF genes expressed in epithelial cells [1].
Breast milk comprises epithelial cells, colostral corpuscles, polymorphonuclear leukocytes, mononuclear phagocytes and lymphocytes [18], [19], with those of epithelial lineage forming the main bulk of cells within two weeks of establishing lactation [20].
In contrast to CD24+ cells, CD24− cells, either sorted from the bulk population or cloned, expressed low or undetectable levels of epithelial markers (E-cadherin and β-catenin) and high levels of mesenchymal markers (vimentin and fibronectin), suggesting that they underwent an EMT (Figure 3C).
Thus, in order to define the cellular origins of the proteases identified from the comprehensive gene expression profile from bulk prostate tissue specimens, we undertook analysis of primary cultures of epithelial and stromal cells from radical prostatectomy tissues.
II Partial flattening of epithelial cells (arrows).
I Good condition of epithelial cells.
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