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The phrase "built upon the brain" is correct and usable in written English.
It can be used in contexts discussing concepts, theories, or systems that are based on cognitive processes or neurological foundations.
Example: "The new learning model is built upon the brain's natural ability to adapt and grow."
Alternatives: "based on the brain" or "founded on the brain."
Exact(1)
"We have frequently argued that many aspects of spiritual experiences are built upon the brain machinery that is used for other purposes such as emotions," he says.
Similar(59)
This paper builds upon the previous Brain Machine Interface (BMI) signal processing models that require apriori knowledge about the patient's arm kinematics.
It is not built upon the premise of trust.
Welch built upon Jones' successes, as Jones built upon the good work done by earlier CEOs.
PkuAS is built upon the JMX specification [29].
The legal settlement also created the C8 Science Panel, which built upon the cohort constituted during the C8HP.
Third, the classification rules are built upon the existing overall pattern of radiotherapy practice.
The fast subtree algorithm is built upon the Weisfeiler-Lehman test of isomorphism [ 28].
The "Vertebrate"/ Vertebrate_relaxed" and "Bilateria"/"Bilateria_relaxed" versions were respectively built upon the same collections of profiles.
The network is built upon the input gene list, curated ChIP, PPI, and Logof data.
However, the global optimal solution is built upon the maximum weighted matching (recall Corollary 3).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com