built into the density

USAGE SUMMARY

The phrase "built into the density" is correct and usable in written English.
It can be used in contexts discussing physical properties, structures, or concepts where density is a relevant factor. Example: "The unique characteristics of the material are built into the density, allowing for enhanced durability."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

7 human-written examples

Most of the residues were automatically built into the density map and the remaining residues were manually built using the graphics package O [24], followed by the structural refinement using the program CNS [25].

Plosone

Rev subunits were then built into the density with iterative model building and refinement.

eLife

All three subunits of Sec61 are present, and have been unambiguously built into the density, including many amino acid side chains in the essential Sec61α and γ subunits.

Cell

The resulting σ-weighted 2 Fo – Fc map showed clear densities for the rest of the protein that were built into the density by COOT.

Biochemistry

The inhibitor molecule was built into the density in all active sites and further refined with Refmac5. 2 Fo – Fc maps calculated from the refined model confirmed the covalent attachment to Ser64.

Biochemistry

The fold inferred from the known stereochemistry of the final products was built into the density followed by a final round of refinement using CNS to produce the current models of the farnesyl chain (Supplementary Figure S5).

ACS Chemical Biology

Human-verified similar examples from authoritative sources

Similar Expressions

53 human-written examples

Initial refinement was carried out with the program CNS and mutations were gradually built into the electron density, followed by further positional and isotropic B-factor refinement.

Plosone

136 of 138 residues were automatically built into the electron density and the sequence was assigned by the program ARP/warp [61], and the remaining N- and C-terminal residues were manually modeled into the electron density via the program COOT [62].

Plosone

The ligand was then built into the electron density using the program COOT and the model subjected to alternating cycles of refinement and rebuilding.

Biochemistry

Models for the three MIT molecules in the asymmetric unit were initially built into the electron density and the ULK3 IST1 models were rebuilt de novo in Coot (Emsley et al., 2010) and refined in PHENIX.

eLife

A long molecule of polyethylene glycol (PEG) was built into the electron-density maps identified in a long tunnel formed by a crystallographic dimer of AaegOBP1.

Plosone

Expert writing Tips

Best practice

When describing scientific models, use "built into the density" to specify where components are placed within an electron density map.

Common error

Do not use "built into the density" when describing abstract concepts where density is not a relevant physical attribute. Instead, choose more appropriate phrasing like "incorporated into the structure" or "integrated into the framework".

Linguistic Context

The phrase "built into the density" functions as a prepositional phrase, often used to describe the placement or integration of a component within a defined electron or physical density. Ludwig examples confirm its usage in describing structural biology models.

Expression frequency: Uncommon

Frequent in

Science

75%

News & Media

13%

Encyclopedias

4%

Less common in

Formal & Business

0%

Social Media

0%

Reference

0%

Ludwig's WRAP-UP

The phrase "built into the density" is primarily employed within scientific contexts, particularly in fields like structural biology, to describe the integration of molecular models into electron density maps. Ludwig AI analysis affirms its grammatical correctness and common usage within formal, scientific discourse. While not as prevalent in everyday language, its precise meaning ensures clear communication in specialized fields. When using this phrase, consider the context of density and whether a more general term like "integrated into the structure" might be more appropriate outside scientific discussions.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

integrated into the density

Replaces "built" with "integrated", emphasizing incorporation.

incorporated within the density

Substitutes "built" with "incorporated", stressing inclusion.

embedded in the density

Uses "embedded" instead of "built", highlighting enclosure.

constructed within the density

Emphasizes the creation or formation aspect within the given density.

designed into the density

Focuses on the intentional design aspect related to the density.

inherent in the density

Highlights that the quality is a natural part of the density itself.

intrinsic to the density

Similar to 'inherent', stressing the essential nature related to density.

part of the density's structure

Rephrases to emphasize that the feature is structural within the density.

a feature of the density

Simplifies to indicate the element is simply a characteristic of the density.

present in the density

A more general way to say that something exists within the density.

FAQs

How is "built into the density" typically used in scientific contexts?

In scientific research, particularly structural biology, "built into the density" usually describes how a molecular model is fitted into an electron density map derived from experimental data, like X-ray crystallography or cryo-EM.

What does "built into the density" mean in the context of structural modeling?

It refers to the process of manually or automatically fitting a theoretical or known atomic structure into a visual representation of electron density, ensuring the model conforms to experimental observations. This is often done using software like COOT.

Are there alternative phrases to "built into the density" that might be more appropriate in different contexts?

Yes, depending on the context, alternatives such as "integrated into the density" or "incorporated within the density" may be more suitable. The key is to choose a phrase that accurately reflects the relationship between the component and the density.

When is it inappropriate to use the phrase "built into the density"?

It would be inappropriate to use the phrase in contexts unrelated to physical or electron densities, such as describing features of a business plan or a social structure. In those cases, consider alternatives like "integrated into the system" or "a core aspect of".