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In this approach, a similarity kernel between the proteins is computed and then a classifier is built by maximizing the margin between the proteins that perform a particular function and those that do not.
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The underlying data behind published studies are also typically kept hidden while researchers try to build their careers by maximizing the number of new discoveries they can get out of the data they produced.
The ML method trains the CRF or CNF model parameters by maximizing the observed probability of a set of reference alignments built by a structure alignment tool.
This is achieved by maximizing the margin between the classes.
"There is a profound conflict of interest built into the industry's structure," he wrote, "one that grows out of the fact that the management companies are independently owned, separate from the funds themselves, and managers profit by maximizing the funds under management because their fees are based on assets, not performance".
They responded by maximizing the number of lines they wrote.
He's a master of appearances, maximizing his influence by maximizing the number of eyes on him.
Parameters are estimated by maximizing the likelihood of the model.
The model was fitted by maximizing the log-likelihood.
Built to maximize the real estate value of waterfront properties, that very proximity has proven toxic due to global warming and sea level rise, made acutely palpable by Hurricane Sandy.
The new district, some two dozen city blocks and counting, will be built to maximize the number of serendipitous collisions among strangers, and would-be entrepeneurs will be measured by their Return On Community more than their return on capital.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com