Your English writing platform
Free sign upSuggestions(5)
Exact(6)
Based on the cryo-EM density, we built an atomic model that allows for interpretation of the structure in great details.
Based on this crystal structure, we have built an atomic model of the enzyme in complex with the substrate DHNP (EcDHNA DHNP) and performed molecular dynamics (MD) simulation of the enzyme:substrate complex.
Therefore, although we built an atomic model with the C-terminal domain contacting the nearest N-terminal one, the positions of the C-terminal domains may be swapped between the two Gins51 subunits to those in the tetrameric structure.
Based on the density map, we built an atomic model, which suggests that SmpB interacts with the five nucleotides immediately upstream of the resume codon, thereby determining the correct selection of the reading frame on the ORF of tmRNA.
To understand the structural basis for the biochemical differences and further investigate the catalytic mechanism of DHNA, we have determined the structure of EcDHNA complexed with NP at 1.07-Å resolution [PDB 2O90], built an atomic model of EcDHNA complexed with the substrate DHNP, and performed molecular dynamics (MD) simulation analysis of the substrate complex.
To interpret the density of the tmRNA, we built an atomic model of the tmRNA using homology and ab initio modelling techniques, starting from 2D structural alignment and X-ray structures of homologous domains deposited in the PDB (see Experimental Procedure and Supplementary Figure S5).
Similar(54)
With a map at 4 Å resolution or better, it may be possible to build an atomic model with the methods used in X-ray crystallography(15).
As a more realistic test, we tried to build an atomic model of the GroEL/ES complex by fitting 21-subunit atomic models into the 3D density map obtained by cryoelectron microscopy using the C7 symmetric restraints.
As a more realistic test, we tried to build an atomic model of the GroEL/ES complex by fitting 21-subunit atomic models into the 3D density map obtained by cryo-EM, using C7 symmetric restraints.
A comparison of the results obtained with a dynamic model of mutual arrangement of s4U77 of the A site tRNA and nucleotides of 23S rRNA built on the basis of an atomic model for the prokaryotic PTC led to the conclusion that environments of the tRNA 3′-terminus in prokaryotic and eukaryotic ribosomes share a significant extent of similarity, although pronounced differences are also detectable.
Thus, the resolutions of the NCPV and TCPV were not sufficient to allow the authors to build an accurate atomic model.
More suggestions(17)
built an additional model
built an iPod model
built an economic model
built an excess model
built an approximate model
built an improved model
built an atomic bomb
built an integrated model
built an international model
built an initial model
built an acceptable model
built an adjusted model
built an ensemble model
built an internal model
built an amazing model
built an electronic model
built an explanatory model
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com