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Using our scoring function calculated on the Portal protein alone, we built a tree of all the Aclame phages (Additional file 1: Figure S5A).
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MetaTree builds a "tree-of-trees" that shows the relationships between alternative phylogenies.
It may be much more efficient to build a tree of conglomerate objects rather than construct the tree for an enormous list of primitives.
Current top-down phylogenetic strategies used to build a tree of life generate unrooted trees and use deep taxa as outgroups a posteriori to root phylogenies.
One such example is Daubin and Galtier's recent proposal to build a tree of life by dismissing the plethora of incongruences in molecular data.
Daubin and Galtier are suggesting that calculations of the mean phylogenetic signal of incongruent genes are the best way to build a tree of life because it integrates (in reality, averages) a large amount of incongruent data.
Here we build a tree of life using a census of FSF domains in 420 free-living (FL) proteomes and employ an iterative strategy to reconstruct the urancestral proteome.
This core-genome included 677 protein families (supplementary table S3, Supplementary Material online) and was used to build a tree of the 135 complete genomes using the method mentioned above for the genus.
SVG takes a scene graph approach (i.e. the rendering code builds a tree of objects describing what should be drawn, rather than calling rendering primitives directly), which means that smooth scrolling and export of high-quality vector graphics in SVG or, with some straightfoward server support, PDF format for publication or presentation are both straightforward.
In the end, he says, "we had to build a tree to meet the needs of the harvester".
Although there is no simple algorithm today to build a tree from tens of thousands of sequences, it would be interesting to study the phylogenic tree of our pool of sequences in parallel with our synthetic lethality study.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com