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Current efforts are directed towards building a preclinical model to evaluate the effectiveness of this approach.
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Here, we deleted Ap4 in ApcMin mice, a preclinical model of inherited colorectal cancer.
The human HCC1806 cell line is frequently used as a preclinical model for triple negative breast cancer (TNBC).
Turnbull, I. C. et al. Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium.
Mesenchymal stem cells (green) colonize a pancreatic islet in a preclinical model of diabetes.
Real-time monitoring of tumorigenesis, dissemination, & drug response in a preclinical model of lymphangioleiomyomatosis/tuberous sclerosis complex.
The present study shows that inactivation of Ap4 by deletion leads to decreased adenoma formation in ApcMin mice, which represent a preclinical model of familial adenomatous polyposis (FAP 9,10.
Here, we aimed at assessing the antineoplastic effect of copanlisib and its potential as a sensitizer to the effect of sorafenib in a preclinical model of HCC.
Marta's work at Stanford is currently focused on development of a preclinical model in which to study radiotherapy and anti-HIF therapies.
As it is quite complex to study responses of metastases in a preclinical model, there have not been many preclinical studies on therapies in metastatic models.
The 22Rv1 cell line is a preclinical model mimicking the progression towards CRPC.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com