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After learning the BN structure, we topologically sort the nodes of the graph and then, start building a classifier for each node in this order (see Fig. 4).
A necessary step when building a classifier for high-dimensional data is feature selection.
To the best of our knowledge, PUDI is the first to design a novel multi-level PU learning algorithm for building a classifier for disease gene identification.
This is accomplished by first building a classifier for each separate source domain.
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Thus, 10-PS were considered the limit for building a classifier of acceptably high and robust predictivity (Fig. 7a).
Development of a biomarker classifier involves two distinct components: (1) a procedure for building a classifier and (2) validation/evaluation procedure for estimating the error rate of biomarker.
For building a classifier, meaningful information of each observation has to be extracted, which is achieved by appropriate features.
At the same time, the re-defined extended cutoff strengthens the correlation between the re-defined endpoint and gene expression profile significantly, thereby providing a solid fundament for building a classifier with higher performance.
One-class uses only the information for the target class (positive class) building a classifier which is able to recognize the examples belonging to its target and rejecting others as outliers.
(ii)Building a classifier.
One of the major problems in building a classifier is the non-availability of labeled data.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com