The changes might also reflect the build-up of genetic load due to a reduction of recombination as predicted by classic supergene theories of polymorphic mimicry.
In particular, the observed build-up of genetic load might be facilitated by a decrease, and not increase, in the rate of inbreeding.
Except for one Dutch herd, prevalence in sows increased in the Dutch herds during time in the farrowing compartment, which might be explained by a build-up of bacterial load, i.e. the infection pressure, during time spent in this compartment.
After the 2003 bushfires, cattlemen such as Cochran suggested the fire was a result of the build-up of fuel loads caused by the removal of grazing all those years ago.
Traffic emissions contribute significantly to the build-up of diffuse pollution loads on urban surfaces with their subsequent mobilisation and direct discharge posing problems for receiving water quality.
Selfers do not suffer the cost of having male offspring that cannot have offspring on their own [ 1- 3], and selfing lineages always segregate more homozygous progeny, which in large populations allows selection to prevent the build-up of the genetic loads responsible for inbreeding depression [ 4- 6].
Longitudinal amyloid PET imaging in large at-risk and patient populations has shown that it takes ≈ 20 years for build-up of pathological amyloid plaque load in the brain [ 13].
Conceivably, this temporal dependency might relate to hypothermia-mediated proteostatic priming, elicited prior to the build-up of a significant protein aggregate load.
The clay pumping occurs under the action of cyclic loading (train loading) due to the build-up of excess pore water pressure.
(If you do this after each load, they won't get an accumulated build-up of gunk and grime).
A periodical build-up of these structures is not ideal, because of the appearance of unfavorable load cases like bending or shearing inside the struts.
