Sentence examples for build the alignment from inspiring English sources
Interestingly, using only sequences of different LGI family members to build the alignment, ConSurf identifies a highly conserved circular region in the top face of the β-propeller.
Conversely any algorithm which uses a phylogenetic tree to build the alignment will be susceptible to hierarchical clustering of misaligned sequences, which are easier to detect.
Resulting hits were then used as tags to build the alignment around (see below).
Anchors derived from this method can be very short since the refinement procedure used to build the alignment graph will produce segments as short as a single base per sequence, such as in the case of a single base indel.
A total of 60 species was chosen to build the alignments.
downloaded all complete genome sequences of Bacteria, Virus from NCBI ftp site ftp://ftp.ncbi.nih.gov/genomes/; removed the plasmid sequence and any other non-human-related sequence; kept only one best genome sequence representing every species based on the assembly result; built the alignment index of reference sequence for classing sequence reads.
If killer options exist simply as a broad venture-capital-like portfolio, without CEO backing, it's impossible to neutralize naysayers until the appropriate time, build the necessary alignment or guide the organizations through the necessary transitions.
As all identified trGTPases were found to carry the G domain and domain II-homologous regions, the sequence region used to build the MAFFT alignment on which the superfamily tree was built was extended to encompass both these domains (an average length of 331 amino acids).
Although we attempted to do the same for the other insects investigated, synteny between them was not sufficient and we were unable to build the necessary alignments.
The approach in principle is very similar to the initialization step of CMfinder to build the initial alignments.
To build the final alignments, we identified homologs of the candidate K. brevis sequences using BLAST searches (e-value ≤ 10-10) aGenBankGenrank nr, dbEST, and public protist databases including the JGI database [ 91], the French National Sequencing Center, Genoscope [ 96], the Protist EST Program database [ 17], C. merolae [ 92, 97] and G. sulphuraria [ 93, 98] databases.
