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These findings led us to build our hypothesis that NuclErbB-2 presence could be associated with highly proliferative breast cancer subtypes which show a poor clinical outcome.
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We built our a priori hypotheses around the emotion of fear for two main reasons.
Researchers estimate that our genes bear only about half the responsibility for our diversity, which supports the old nature/nurture hypothesis: Nature builds our basic personality, and then our environment tinkers with it over the course of our lives.
In order to focus on testing the most probable scenarios, we built up our hypotheses based on the results of the Skyline plot analysis from MIGRATE-n (Additional file 1: Table S4 and Additional file 1: Figure S1).
To build experimental support for our hypothesis that G oxidative damage in G4s recruits the fifth domain, we turned our attention to the VEGF G4.
The foundation of our hypothesis is built on data from artificial bilayer experiments which provide the physical principles by which PUFA acyl chains affect membrane architecture.
To confirm our hypothesis, we built three logistic regression models by successively using the component combinations belong to these HMs: H3K36me3, H3K36me3+H3K9me3, H3K36me3+H3K9me3+H4K20me1, which were referred as three simplified models in the following context.
So we built yohimibine group to test our hypothesis, however, yohimbine failed to reverse the anti-inflammation effect of dexmedetomidine, indicating that the protective effect of dexmedetomidine on CLP-induced septic rats is independent of α2-adrenoceptor.
Generally, you use your study to build a hypothesis; you then test the theory on fresh data.
In the last stage, these PDFs are fed into a classifier to build a hypothesis model.
Thus, these observations strongly suggest the involvement of DELTA-1 mediated signalling on neurogenesis and help to build a hypothesis for its possible implication on the transition from proliferative to neurogenic NP cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com