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To build an affinity reagent that selectively binds the activated state of PAK1, we used molecular modeling to reengineer the isolated IS domain so that it was soluble and stable, did not bind to guanosine triphosphatases and bound more tightly to the PAK1 kinase domain.
Instead, they decided to build a portfolio of products users could identify with and build an affinity toward.
The truth is that to stand out in the crowded marketplace of marketplaces for services, the company has to build up a reputation of phenomenal customer service and have a brand that people build an affinity for, which is no small task.
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A training set of 76 podophyllotoxin analogues was used to build a binding affinity model for estimating the free energy of binding for 36 inhibitors (test set) with diverse structural modifications.
The goal of these events is to build a strong affinity between the community and your organization.
He said this strategy was designed to persuade British fans not only to attend games in the UK, but to build up an affinity with one of the regular participants.
York, who is also head of the NFL owners' international committee, explained that this strategy was designed to persuade British fans not only to attend games in the UK, but to build up an affinity with one of the regular participants.
This approach enabled the authors to build a shape-to-affinity model from the shape parameters derived from unmethylated sequences of the form NNN|CGN, as well as to predict, for each DNA sequence, the change in binding free energy associated with methylation of the CpG dinucleotide downstream of the cleavage site.
"So much of the net new workloads that are being built have an affinity for Linux".
On other occasions, brands pay Vimby to create content that the advertiser can use to build an online community or cultivate greater affinity with its consumers.
Dyson uses social media tools to engage alumni and build a network of graduates with a shared affinity for the school.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com