The level of detail necessary to build a constraint-based model of a bacterium's metabolism is relatively low; the only information required is the precise reaction stoichiometries and directions, in order to account for mass balance and irreversibility constraints.
First it considers the gap constraints and builds a constraint graph whose nodes are the simple motif occurrences and edges connect all possible pairs of nodes that locally satisfy the gap constraints.
In an effort to enable the analysis of P. putida KT2440 from a systems biology perspective and to foster the development of its biotechnological applications, we built a constraint-based metabolic reconstruction (iJP815) of this strain [ 8, 9].
Interestingly, for PG it is possible to build a network up in constraint density through a bootstrapping method by first placing a certain number of constraints at random, and then adding more constraints.
As is the case for other CAD/CAE integrated systems (e.g., IsoGeometric Analysis (IGA)), the designer is only required to build a CAD model, define constraints and adjust designs.
In addition, federal regulators are moving to create a more open national wireless network when it auctions off spectrum licenses in January that would allow bidders to build a network free from carrier constraint.
Therefore, the only constraint to build a similar type of sensor is to find a region of the aptamer that could be replaced by or incorporated with an antisense element.
The proposed framework makes use of a graphical representation of the world in order to build a map consisting of qualitative constraints on the geometric relationships between landmark triplets.
However, the superiority of the German compelled the Imperial Navy to lift cost and size constraints and build a large battleship with two main gun turrets.
The situation reminds me of "Moneyball," the 2003 book by Michael Lewis and later movie about Oakland A's general manager Billy Beane and his embrace of statistical analysis to build a winning team despite salary constraints.
The resulting experimental data, along with all the rest of structural data existing at hand in the literature are introduced as imposed constraints to build a 3D-model of the ERK2−PTP-SL ERK2−PTP-SL
