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This finding suggests a buffered response to structural changes induced by CNVs and implies that heterozygous masking effect may protect genes from harmful consequences.
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It was postulated by W.W. Lautt that the hepatic artery flow compensation for changes in portal vein flow (the 'hepatic arterial buffer response') is regulated through the portal blood washout of adenosine from the small fluid compartment that surrounds the hepatic arterial resistance vessels.
Of nine species and guilds, none appeared to benefit from 50 m riparian buffers, response to an unmanaged scenario was mixed and expensive, and block-size restrictions (maximum harvest unit size) provided no apparent benefit and in some cases were possibly detrimental to bird richness.
This mechanism is called hepatic arterial buffer response and appears to be mediated by adenosine [88].
Both autoregulation of hepatic artery and hepatic buffer response appear to be impaired [90].
We found that in patients undergoing portal vein ligation and parenchymal transection, portal vein hyperflow in the regenerating liver causes a significant reduction of arterial flow due to the hepatic arterial buffer response.
Early fibrosis associates deposition of collagen in the Disse space with alteration of the sinusoidal architecture, resulting in a decreased portal venous flow, which is counteracted by an increase in hepatic arterial flow (buffer response).
HABR = hepatic arterial buffer response.
CPB = cardiopulmonary bypass; HABR = hepatic arterial buffer response.
TEA reverses hepatic hyperperfusion in late sepsis, probably by restoring hepatic arterial buffer response.
This mechanism known as hepatic arterial buffer response maintains the total liver blood supply [ 45].
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