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the pH of the buffer was optimized by Xu et al., who found that the peak-to-peak potential separation is the lowest at pH 7.0 [27.0
The rheological profile of a biosimilar mucus mixture composed of purified gastric mucin, lipids and protein in buffer was optimized by supplementing with an anionic polymer to display viscoelastic properties and a microstructure comparable to freshly isolated porcine intestinal mucus (PIM).
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Conditions of analysis, including ligand immobilization, dilution ratio of milk, salinity, and pH of the dilution buffer were optimized by Doehlert experimental design in order to enhance the detection specificity.
To maximize the efficiency of the Direct PCR, the ratio between sample and dilution buffer was optimized.
In the present study, the oxidation peak current of dopamine (DA) in a 0.2 M Britton Robinson (B R) buffer solution was optimized by experimental design for its determination in the presence of tyrosine (Tyr) at the surface of graphene oxide modified carbon paste electrode (CPE/GO).
The derivatization of four targeted amino acids proceeded with 80 μmol/L TMBB-Su in 10 mmol/L mixed acid buffer (pH 7.20) at 25 °C for 25 min, which was optimized by orthogonal array design.
Concentration and composition of the starting buffer were optimized as well.
Resolution was optimized by deconvolution microscopy software.
The structure resulting from the averaging was optimized by EM.
The threshold was optimized by combining multiple benchmarks (see below).
Finally, the tumor image was optimized by a morphology operator.
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