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However, a strong robustness may buffer the accumulation of beneficial mutations.
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Calbindin D28K is commonly described as a neuronal calcium buffer that prevents the accumulation of toxic levels of calcium via four calcium binding domains [34], [35].
Our data suggest that imbalance of visceral and subcutaneous fat distribution, i.e. increased visceral fat with decreased subcutaneous fat accumulation, is an important determinant of atherosclerosis, whereas increased subcutaneous fat accumulation could buffer the deleterious effect of visceral fat accumulation in patients with type 2 diabetes.
It is postulated that by regulating an entire cellular program through the cooperative repression of target genes, miRNAs may serve as buffers to limit the accumulation of many gene products that impact cell cycle progression under a variety of contexts[28].
In this assay, E. coli cells are resuspended in 25 mM citrate buffer, pH 2.5, and the accumulation of ammonium ion is monitored by a specialized ammonium meter.
Transition preparation efforts encompassed staff training to prepare people for the transition, alignment of both clinical and administrative structures, as well as the accumulation of buffer stocks in case of a gap in supplies and financial reserves at the time of transition.
The lead ions in the buffer combine with Pi, which results in the accumulation of lead phosphate, a grey precipitate where the Complex V band is present.
Job resources buffer the impact of job demands on burnout.
An intermediate behavior was evidenced in borate buffer for which a slow repassivation ascribed to the accumulation of insoluble corrosion products inside the pit was observed.
The accumulation of animals as a buffer against future loss has been argued to be an efficient strategy for countering risks (see e.g., Hjort 1981; Templer et al. 1993; Næss 2009).
The UPR is activated upon the accumulation of misfolded proteins and buffers the ER stress.
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