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The kidneys from such embryos showed effects ranging from those with severely reduced and morphologically abnormal branching and growth to those with more normal ureteric bud trees.
It is important to note that some nephrons within the ureteric bud trees of Apc+/1638N Ctnnb1+/E654 mutant animals still managed to produce proximal domains.
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Yellow and red dashed circles indicate ureteric bud tree-bound endogenous and ectopic nephrons, respectively.
Dashed line indicates separation between ectopic and endogenous ureteric bud tree-bound nephron structures.
A few endogenous nephrons within the ureteric bud tree managed to produce proximal domains.
Dashed line indicates separation of ectopic nephrons from the ureteric bud tree and endogenous 'tree-bound' nephrons.
Wholemount immunostaining with pan-cytokeratin, to highlight the ureteric bud tree, revealed that branching morphogenesis was severely disrupted in E13.5 Atmin Gpg6/Gpg6 kidneys (Fig. 1E compared with D).
Season of baseball, budding trees and final exams.
Not just for the lambs and the budding trees, but for fashion and trends.
The sun is flat and white and the budding trees cast a blurry shade on the path.
Bedford plants the seeds in a greenhouse, and grafts the budding trees onto outdoor rootstock the following summer.
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