Sentence examples for bse time from inspiring English sources

In our previous BSE time course study, 205 differentially regulated probe sets (corresponding to 114 genes) have been used to show that preclinical animals at 45 months post inoculation (mpi) cluster with cases positive for BSE and allowed the prediction that they are indeed preclinical and close to developing BSE [11].

During this time, BSE transmission among cattle was caused primarily by feeding meat and bone meal derived from other BSE-affected cattle [ 3, 4].

It is difficult to believe that any responsible scientist would have told a minister this.By the time BSE had almost run its course, on the other hand (and after a change of government), a risk of one case of nvCJD per billion people was enough to cause the sale of beef on the bone to be banned.

All cattle were purchased from UK farms with no history of BSE at the time of sourcing.

In study 2 [ 16], 63 groups of five Friesian or Friesian crossbred castrated male calves from UK farms with no history of BSE at the time of sourcing were inoculated intracerebrally.

Control animals did not exhibit any BSE symptoms at the time of collection and were age matched with BSE cases from the same farm.

Thus, the proportion of vCJD cases due to exposure to indigenous BSE may increase with time.

For Tg 338 mice, the mean incubation period was 239 ± 32 days for the atypical scrapie isolate, and the incubation time for BSE prion previously passaged through ARQ/ARQ sheep was 534 ± 25 days.

The display of several BSE-associated signs over time, including repeated startle responses and nervousness, was significantly more frequent in confirmed BSE cases compared to controls, but these two signs were also significantly more frequent in orally dosed cattle unconfirmed by postmortem examinations.

Nonetheless, other studies attribute shorting of incubation times between BSE and vCJD to strain adaptation effects using either intravenous or intracerebral routes of inoculation [14].

However, clinically available bioengineered skin equivalents (BSEs) suffer from a number of drawbacks, including time required to generate autologous BSEs, poor allogeneic BSE survival, and physical limitations such as mass transfer issues.