6. Labour and domestic exposure to possible risk factors of exacerbations: number of persons residing at home, presence of children or other chronic patients at home, presence of pets at home, environmental factors (dust, smoke, humidity, brusque temperature changes, air-conditioning, paint and solvents, combustible products, pollen).
And, in his own brusque way, Losey changed England and its attitude to the movies.
Until the early thirties, Toscanini was mainly known as a conductor of brusque brilliance who changed his profession from a gentlemanly calling into a priesthood.
If the unveiling of a handsome statue of Duncan Edwards in Dudley this week represented one admirable dimension of English football, the storm of bile that broke over Arsène Wenger's head following his club's home defeat by Olympiakos on Tuesday provided a brusque reminder of the changes inflicted on the English game in the past 50-odd years.
He'll think, 'That's not right, I should have told her, it should have been changed.' " "Charles may seem brusque," explains Simon Keenlyside, "but what he's waiting for is you to present him with things and to be able to deliver them.
"People say this is a paradise, but the changes have been so rapid and so brusque that I fear we may have already gone past our natural limits".
This practice was inspired by the way the music of Ludwig van Beethoven changed over the course of his life; brusque and dynamic, even aggressive, during his middle age, it turned inward and became profoundly mysterious in the decade before his death.
As former secretary of state Henry Kissinger explains, Bismarck changed the map of Europe "with a few brusque strokes [that] swept away the dilemmas that had baffled the German quest for unity". He polarized but nonetheless defined the fate of European history.
Its tones change swiftly, almost imperceptibly: they are in turn ironical, impertinent, brusque, laconic, eloquent, compassionate, melancholy, or reflective.
On Friday evening, Mr. Monti handed in his resignation to President Giorgio Napolitano, who in a tough speech to lawmakers last week lamented the "brusque" end of the government and Parliament's failure to carry out significant structural changes in Italy's encrusted economy.
