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The development of Guam into an important U.S. military base brought about profound changes in the island's agricultural patterns after World War II.
California's struggle with air quality, particularly in the Los Angeles Basin, brought about profound changes; in 1966, the state was the first to require smog equipment, and it wasn't long before the federal Clean Air Act clamped down.
Rapid urbanization and spontaneous economic development has brought about profound changes in urban landscapes throughout the world.
The professionalisation of university curricula has brought about profound changes in the traditional academic education concept and faces the introduction of more professional courses into university systems.
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Many economists also argue that the growing dominance of finance, accelerated by the Big Bang, helped to bring about profound changes in the UK's economic model.
"A very simple clarification [of the amendment] on paper would bring about profound change, not just for women in Kenya, but for women around the world".
The Environmental Protection Agency, a federal body, also raised concerns about "potential risks" to the watershed.The path of demand in gas's new age is hard to predict, but abundant new sources could bring about profound change in patterns of energy consumption.
Hugh Hudson took on the Education portfolio, an important role in a government that was determined to bring about profound change to the South Australian education system.
What appeals to me about filmmaking is that it extends the conversation and has the power to inform and bring about profound change.
And for the last two decades the Internet brought about profound change.
From time to time, it has been accused of straying from its original mission and trying ineffectually to bring about profound social changes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com