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Our transcriptional analysis on rice and sorghum revealed that the expression of trihelix genes within various clades was broadly stimulated by abiotic stress (Fig. 4), which implies that the functional involvement in abiotic stress resistance within this family might be conserved in grass.
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Commenting on the widespread push to encourage more students to study STEM in order to boost the economy, the report notes that "public policy to broadly stimulate the number of STEM graduates will have no direct effect on the overall economic performance of Indiana, and risk[s] suppressing the wages or increasing outmigration of future STEM graduates".
This experimental protocol was devised with the goal to broadly stimulate both the innate and the adaptive components of the immune system for a protracted period of time.
The same is true for the E2 experiment; however, it is well known that E2 broadly stimulates proliferation of pituitary cells (Castrique et al., 2010; Nolan and Levy, 2009).
Furthermore, there is strong evidence from animal data that a whole host of agents that broadly stimulate the immune system are effective in reducing significantly the incidence of tumour metastases and the growth of tumours after surgery.
Conversely, keeping animals in an enriched environment, which broadly stimulates motor, sensory and cognitive systems, increases the turnover, i.e., both the formation as well as the elimination of dendritic spines and this turnover.
More broadly, Microsoft's anticompetitive actions trammeled the competitive process through which the computer software industry generally stimulates innovation and conduces to the optimum benefit of consumers".
Perhaps not surprisingly, multiple factors (that is, strength and duration of PR phosphorylation, transcriptional activity, and protein levels) likely influence the kinetics of PR-regulated MAP1A expression in cells stimulated broadly with growth factors.
The broadly cross-reactive antibodies stimulated from the overlapping immunodominant epitopes surrounding the EDII fusion peptide are predominantly non-neutralizing as evidenced by the general lack of cross-protection between the flaviviruses [7], [8], [9], [10], [19], [26].
Fruitflies heterozygous for a null mutation of Rop, the Munc18 homologue in Drosophila, also showed a marked reduction in synaptic vesicle release [ 54], suggesting that Munc18 protein expression is limiting for stimulated secretion broadly across isoforms, cell types and organisms.
We hypothesized that peptides representative of the diversity of natural HIV-1 V3 loop variants might capture elements of conserved higher order structures and so stimulate broadly reactive neutralizing antibodies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com