Importantly, most ORs are broadly tuned responding to a range of chemically similar odorants [33].
In the bristletail L. y-signata, we found that many of the OSNs are very broadly tuned, responding to volatiles with several different functional groups at higher doses.
This either implies that the ratio of E11 versus Z11 sensitive OSNs in the E-strain is similar, or that the E11 receptors are more broadly tuned (responding also to Z11) than the Z11 receptors (responding less or not at all to E11, [ 19, 42]), or both.
Peripheral blood mononuclear cells (PBMC) are composed of circulating immune cells including lymphocytes, monocytes, and dendritic cells that are rich in TLR expression[11] and respond broadly to TLR ligands.
In contrast to Ors, which respond broadly to alcohols, ketones, and esters, Irs primarily respond to acids, amines, and carbon dioxide, which can be physiologically important in many insect species [ 77, 86– 86].
How does AT&T respond most broadly to this new being?
As comedian Kumail Nanjiani said, "Comedians making transphobic jokes: What side do you wanna be on?" TJ Miller's agent did not respond to Broadly's phone and email request for comment.
These results are similar to recent electrophysiological data finding that the large-spiking neurons of ECB(E) males actually respond more broadly in vivo [22] [23].
Neuron 4 responded broadly to gratings of between 225° to 45° and was significantly orientation tuned (py = 0.042).
