Kriebs, A. et al. Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity.
"It doesn't go the whole way but it allows you to broadly interact with a lot of different people and get the first step of every plan in place," explains Matt Capucilli, the founder of Reddyset, the application development company that produced Ketchup.
To determine whether LRRK2 broadly interacts with members of the dynamin superfamily, we compared the interaction of LRRK2 with the classical dynamins, Dnm1, Dnm2 and Dnm3, by co-IP in HEK-293T cells expressing FLAG-tagged LRRK2 and full-length HA-tagged Dnm1-3.
Furthermore, cell wall Hsp60 more broadly interacts with enzymes related to carbohydrate metabolism, suggesting a trafficking function of the Hsp60 related to enhanced energy acquisition under stress conditions.
Moreover, FER is also broadly speculated to interact with cell wall carbohydrates by virtue of its extracellular homology with the disaccharide-binding malectin (Kessler et al., 2010; Cheung and Wu, 2011; Lindner et al., 2012; Wolf and Hofte, 2014).
I was worried about what is was doing to my relationship and it got me thinking more broadly about how I interact with food.
I was worried about what it was doing to my relationship, and it got me thinking more broadly about how I interact with food.
However, Gal-1 is constitutively expressed in most organs [5], showing that Gal-1 broadly, but also nonspecifically, interact with the immune system.
On the contrary, the large cluster #2 contains mainly Treponema or Spirochete specific proteins, which interact with broadly conserved proteins, and is enriched for proteins of unknown or general function (3 fold, p = 0.003).
Participatory diagramming required interviewees to think broadly about who oncologists interact with, capturing more unique relationships and positions/organizations (not identified through our literature review or document analysis and therefore not depicted in Diagrams B/C).
Thus detection of diversifying selection is not limited to host response modifying genes but more broadly to genes whose products interact with the host, such as major antigens.
