Sentence examples for broadly implicating from inspiring English sources

Altogether, we introduce evidence broadly implicating mutations within a diverse set of zinc finger proteins as relevant for cancer, and propose that they contribute to the widespread transcriptional dysregulation observed in cancer cells.

However, when asked about specific personnel, such as the nurses, the participant's employer in prison or prison education officers, many inmates were more reflective and considered staff as individuals rather than broadly implicating all staff within the correctional system as not being trustworthy.

But the issue of identity and loyalty sweeps far more broadly, implicating debates about the political safeguards of federalism, the ability of states to check national power, and the likelihood that states will produce policy innovations or good opportunities for citizen participation in government.

Deregulation of microRNAs has been broadly implicated in the inactivation of tumour-suppressor genes and activation of oncogenes in HCC.

Spatial thinking subsumes various cognitive operations of visualizing and operating on spatial information, but it also more broadly implicates the tools and processes of reasoning that situate such cognitive competencies.

BACKGROUND The prefrontal cortex plays a critical role in regulating emotional behaviors, and dysfunction of prefrontal cortex-dependent networks has been broadly implicated in mediating stress-induced behavioral disorders including major depressive disorder.

Natural antisense transcripts (NATs) have been broadly implicated in regulating gene expression and chromosome structure [29] [34].

Decreased expression of Ppara has also been observed in aging heart, liver, and kidney [72] and recently it has been broadly implicated in aging and systemic inflammation [73].

In addition to effects on eicosanoid metabolism TGM2 also activates the transcription factor NFκB that is broadly implicated in the generation of pro-inflammatory cytokines in asthma and other inflammatory diseases, and induces iNOS via NFκB [42].

The fact that positive correlations between RT and BOLD amplitude were found primarily in frontal regions is consistent with the conventional wisdom that MFC and lateral PFC regions are central components of a cognitive control network broadly implicated in supporting effortful, goal-directed activity [40], [41].

These observations broadly implicate plasma membrane potassium, sodium, and calcium transport as important to activity.