It can be credited with the discovery[ 3] (or rediscovery) [ 4] of the basal subtype, and, more broadly the identification of subtypes of breast cancer that hold out the potential to inform clinical practice [ 3, 5- 8] Despite its utility, the standard script suffers from several limitations, in particular the instability of the binary tree of the clusters found [ 9].
To the extent that this data will be accessible broadly, re-identification risk assessments should be considered because this represents information on one third of the US population, which is a much larger sampling fraction than for the Canadian ADE database.
Rather, his defense of the pragmatic approach to a theory of knowledge or of truth gave pride of place to a pragmatic theory of knowledge, interpreted broadly as the identification of truth with prediction and the instrument by which the human mind was able better to predict and control its environment or more successfully to resolve the problems and conflicts it encountered and experienced.
Triage is a key step in the biocuration pipeline and, broadly speaking, involves identification of specific data types for curation.
More broadly, the correct identification of independently evolving lineages (species) is of critical epidemiological relevance, as it can enable interbreeding populations to be identified, which is essential for the management of disease [ 30].
Identification of broadly cross-reactive HIV-1-neutralizing antibodies (bnAbs) may assist vaccine immunogen design.
We anticipate that the cell-based aptamer selection approach used here will be broadly applicable to the identification of aptamer-based agonists for a variety of cell-surface signaling receptors.
RNAi HTS technology allows genome-wide loss-of-function screening and is broadly used in the identification of genes associated with specific phenotypes.
It has been anticipated that the identification of broadly neutralizing mAbs from HIV-1 infected individuals, and the characterization of their cognate epitopes will be instrumental in the design of immunogens capable of eliciting such a broad neutralizing response [12].
The use of deep sequencing of the degradome is broadly applicable for global identification of small RNA targets [ 27- 30].
