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Duplicated gene pairs sometimes have contrasting expression patterns, such that one gene is broadly expressed in a wide range of organ and tissue types, whereas the other gene shows an expression pattern that is restricted to only a small number of organ types.
HOIP RNA is broadly expressed in a variety of tissues [22] but relatively little is known about the physiologic function of the protein.
MICA is broadly expressed in a variety of malignancies, including melanoma, breast, colon and hepatocellular cancers [ 6- 8].
I found that all four zebrafish genes were broadly expressed in a wide variety of regions of the adult brain.
The reviewers are correct that believable colocalization can be difficult when the antigens are broadly expressed in a complex neuropil.
It is also broadly expressed in a variety of tumors, including hematologic and epithelial malignancies [ 12, 13], cervical cancers [ 14], and cancer cell lines [ 15, 16].
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Using an Id2-GFP reporter system, we show that Id2 is broadly expressed in all cDC subsets with the highest expression in CD103+ and CD8α+ lineages.
In H. orientale (Chloranthaceae), HoPI was broadly expressed in all floral organs, whereas HoAP3 was restricted to stamens (Liu et al. 2013).
In perianthless C. spicatus, CsPI reported here, was also broadly expressed in all floral organs, but CsAP3 was restricted to stamens (Li et al. 2005).
Cluster analysis showed that most of CCCH genes were broadly expressed in all of tissues examined with various levels.
Clustering analysis showed that most of CCCH genes were broadly expressed in all of tissues examined with various levels.
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