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Temporal variance is a simple and broadly applicable method for analyzing bacterial swarming behavior in two and three dimensions with both high-resolution and wide-spatial coverage.
If hypothermic storage is a simple and broadly applicable method for enhancing cell stability, it also lead to logistic burden linked to the short shelf life of the product.
Here, we present MMDiff, a robust, broadly applicable method for detecting differences between sequence count data sets.
Our results reveal the importance of the cofactor RimP in central PK formation, and introduce a broadly applicable method for characterizing macromolecular assembly in cells.
The cyclization of a pendant amide or thioamide nucleophile onto a degree of unsaturation represents a very direct and broadly applicable method for the synthesis of oxazolines and thiazolines.
Our results provide a single-cell perspective on epigenomic cell-state dynamics in pluripotent and differentiating cells, and a broadly applicable method for studying DNA methylation both in single cells (scWGBS) and in very small cell populations (μWGBS).
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Safe, efficient, and broadly applicable methods for delivering site-specific nucleases into cells are needed in order for targeted genome editing to reach its full potential for basic research and medicine.
Furthermore, broadly applicable methods for efficient construction of defined mutations in phage genomes are lacking, in sharp contrast to the range of approaches that have been described for targeted mutagenesis of bacterial chromosomes[8], [9].
Therefore, the accurate and broadly applicable methods for semen assessment might help to analyze male fertility.
One decade on, there is still a need for broadly applicable methods for systematically assessing intervention needs and impacts [ 2, 3].
We aimed to develop and validate broadly applicable methods for quantifying common spatial patterning across urban chemical and non-chemical exposures.
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