Interestingly, the former scenarios predicted both more drastic expansions and more drastic contractions, as is noticeable in the broader variation in predicted area losses and gains (Figure 2).
This corresponds to the results found in a study by Lieberman et al. [ 16], with a much broader variation in patient age.
In contrast, sera from the common marmosets displayed a broader variation in responses against the two major epitopes C1 and U1, with more negative samples.
In both species, dystrophin loss progressively leads to abundant necrotic myofibres being replaced by mononucleate infiltrates, extensive fibrosis accompanied by inflammation, and broader variation in the size of muscle fibre cross-sectional areas (compared with healthy muscle) (Fig. 2C,C′).
Tumor endoprostheses have broader variation in site, patient age, tumor malignancy, extent of tumor invasion, need for secure margins, patient immune condition, defect size, soft-tissue condition, and prosthesis type than conventional prostheses for total knee or hip arthroplasty.
The progressive degeneration of dystrophic muscles in these disorders is characterized by: abundant small-diameter fibres with central nuclei (indicating regeneration), infiltration of mononucleate cells, accumulating fibrosis and a broader variation in the size of myofibre cross-sectional areas compared with muscle in healthy individuals.
Most broad variations in the topography of the ocean floor, the mid-ocean ridges and rises, are due to horizontal variations in temperature in the outer 100 kilometres of the Earth.
It is observed that for those major events for which the quasi-16-day amplitudes are high, the broad variations in the amplitudes of semi-diurnal tide and the quasi-16-day amplitudes are quite similar.
In contrast to the narrow (Gaussian) distributions of spherule sizes, there were broad variations in aggregate sizes that were approximated by a lognormal probability function with a geometric standard deviation of about 1.8.
