Sentence examples for broader unbiased from inspiring English sources

Our study has taken a broader, unbiased whole-genome approach to identify methylation changes on genes of FGR offspring secondary to poor placental development.

To obtain a broader, unbiased view of the inhibitor's effect on the NOD pancreatic infiltrate, we undertook a transcriptome analysis of the bulk CD45+ cell population.

In parallel to candidate gene analyses, broader, unbiased genome-wide gene expression profiles [ 27] have been used to identify disease-specific signatures and hidden biomarkers in rheumatology with microarray-based methods [ 28].

Thus, in addition to traditional fold change analysis of microarray data for biomarker identification, a broader, unbiased systems-biology approach, such as we have done here, is likely to identify biological changes that can be reliably verified in multiple data sets.

"You need a broad, unbiased sample in order to have valid results," Representative Zoe Lofgren (D CA) said at the meeting.

To our knowledge, this is the first broad unbiased (i.e. not driven by evolutionary conservation) screen for transcriptional enhancers in transgenic mice.

Likewise, another report had subsequently suggested that non-conserved elements could also harbour enhancer activities in zebrafish transgenics [20], but a broad unbiased screen had not so far been conducted in mice.

Thus, universal PBM data provide a broad, unbiased view of the DNA binding preferences of TFs.

This shows higher sensitivity detection of targeted antibody-based assays compared to broad unbiased MS analysis, which is no surprise.

Here we used a broad, unbiased and sensitized screening approach to uncover susceptibility to immune, metabolic, cardiac, cancer, and behavioural phenotypes.

For example, PCA clusters datasets based on broad, unbiased relationships and provides clues about the general types of metabolites predominantly responsible for the variance among samples.