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Broader trials are needed to confirm the results, and it will most likely be years before the product is publicly available, but if produced on a large scale the gel would cost less than 25 cents per application, the lead investigators estimated.
In addition, several other trials in which diabetic patients constituted only subgroups within broader trials of aspirin prophylaxis, yielded conflicting results [ 44– 44].
In summary, the currently available evidence on aspirin for CVD prevention includes three trials conducted specifically in patients with diabetes and six other trials in which patients with diabetes constitute subgroups within broader trials of aspirin prophylaxis.
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Now London's transport authorities are rolling out a broader trial, centred around Southwark.
A detailed analysis &1QJ of the clinical efficacy of treatment of MDS with lenalidomide will be prepared for publication after the broader trial is completed.
But while it may not reveal as much as a broader trial would have, the scheme's designers are confident it will shed new light on several key social policy issues.
As prosecution and defence prepare to call witnesses to support their arguments on sentencing, here are a few thoughts about Judge Masipa's options, and the broader trial: Jail term.
The intervention needed further refinement prior to a broader trial.
Many specific aspects of the broader trial design, including details of randomisation and blinding, are addressed elsewhere in the CONSORT checklist.
We explored whether the type of Network affected the level of activity, but found no consistent pattern; this target was reached ahead of schedule and indeed exceeded, demonstrating that a coordinated and targeted effort can result in increased recruitment, geographically broader trial participation and timely delivery of research studies, while maintaining high standards of research quality.
To simplify a complex matter: there are two sorts of studies that are done on drugs: broad trials and narrow trials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com