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The combination of genetic and epigenetic information in relation to disease risk should allow a broader range of evolutionary hypotheses to be tested, which will in turn have implications for intervention and public health.
However, comprehensive analysis including validation of the present assumptions should become possible when such data become available for a wider range of organisms separated by a broader range of evolutionary distances.
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The results show that the proposed approach is helpful for analyzing a broad range of evolutionary algorithms.
Proteins show a broad range of evolutionary rates.
JF is a herpetologists and is interested in a broad range of evolutionary questions.
These 10 species were chosen because they cover a broad range of evolutionary distance and their genomes are well annotated.
The sequences of all known actins of selected vertebrate species and of muscle-like actins of a number of other species, covering a broad range of evolutionary history, were extracted from GenBank (Supplemental Table 1).
Understanding the properties of new mutations is critical to a broad range of evolutionary theory, including models relating to the maintenance of genetic variation in the face of selection [ 1- 3], the persistence of small populations [ 4], and the advantages of sexual reproduction [ 5- 7].
Gene frequency distributions for almost 400 groups of 10 bacterial or archaeal species each over a broad range of evolutionary distances were fit to steady-state, infinite allele models based on the distribution of gene replacement rates and the phylogenetic tree relating the species in each group.
Nuclear markers (excluding nrDNA marker) are essential for a broad range of evolutionary investigation, including systematics and character evolution [e.g. [ 26]], hybridization [e.g. [ 27]], polyploidization [e.g. [ 28]], biogeography [ 29], origins of domestication [e.g. [ 30]], and speciation [e.g. [ 31]].
In contrast to most molecular studies on corals, the present study finds clear genetic breaks and deep divergence between many congeneric species, which is likely to have resulted from taxonomic sampling across a comparatively broad range of evolutionary divergence, and geographic regions.
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