"Climate change" is often used to encompass that broader range of effects.
IKKα ablation was recently reported to show a broader range of effects on OA chondrocytes, such as enhanced ECM formation, due to the accumulation of collagen II fibers [ 22] and an increased chondrocyte proliferative capacity, a size reduction effect in undifferentiated chondrocytes and an enhanced survival rate of differentiated cells.
QTGENN is used to detect quantitative trait association with a broad range of effect sizes.
Even assuming the normal biological variability, we wonder as to whether this broad range of effect intensities can be justified by changes in the perfusion system.
To determine CI values, the commercially available program CalcuSyn (Biosoft Ferguson, MO, USA) was used to calculate CI values for a broad range of effect levels and, on the basis of this analysis, Fa versus CI plots were generated.
When estimates are scaled to the same exposure increment and time period (Table 4), it is apparent that past and present longitudinal studies have estimated a very broad range of effect sizes on lung function growth.
Significant improvements in a wide range of cardiovascular parameters such as the high frequency component of heart rate variability (HRV), pulse wave velocity (PWV), blood lipid profiles (low density / high density lipoproteins and triglycerides), and C-reactive proteins (CRP) highlights the broad range of effect yoga has on the cardiovascular system [ 37– 45].
Studies have confirmed that statins have a broad range of effects on cells and tissues involved in the inflammation process.
Understanding the broad range of effects of NATs will shed light on the complex mechanisms that regulate chromatin remodeling and gene expression in development and disease.
Obviously, the complex mathematical calculations necessary to represent the broad range of effects often requires a reduction of the detail of technological data input which leads to less detailed results.
