Sentence examples for broader range of binding from inspiring English sources

However, ligand-based approaches often cover a broader range of binding conformations, but only a small part of possible binding site space at the protein, which is a reason to prefer structure based methods.

Low complexity domains, on the other hand, provide a means for more dynamic interactions with a potentially broader range of binding partners (Fig.  2).

Many Tc variants have been produced, both to overcome bacterial resistance and to achieve a broad range of binding strengths.

By the adoption of different experimental strategies (column chromatography, simple partition equilibrium, solid-phase immunoassay and biosensor technology protocols) quantitatiative affinity chromatography can be used to characterize interactions governed by an extremely broad range of binding affinities.

Notably, UBF contains an array of six HMG box domains that exhibit a broad range of binding affinities for DNA [ 69].

They observed a broad range of binding potential and specificity across cell types, implying a high level of variation in cell surface glycans within mammalian cell types.

The binding of protein onto nanoparticles showed a broad range of binding efficiencies, varying in the protein:nanoparticle ratio between 1 to 1.8, and indicating that the activated nanoparticle had attained protein loading saturation.

The protein mutagenesis experiments therefore give a more nuanced view of how EF-Tu achieves its broad range of binding affinities for different tRNA bodies than was previously obtained from tRNA mutagenesis experiments.

The uniquely mapped HLP1-CLIP tags showed a broad range of binding sites to sense targets (1 934 562), encompassing 5′-UTR (2.69%), coding sequences (CDS, 18.61%), introns (23.18%), 3′-UTR (26.11%), intergenic regions (27.03%), pseudogene (0.80%) and noncoding gene exons (1.58%; Figure 2B).

Many enzymes have broad ranges of binding affinity for different substrates that allows them to affect a variety of cellular pathways.

Previous studies have reported the development of in silico QSAR models based on training sets of relatively small and mostly similar compounds; this model covers a broader range of melanin-binding affinities than what has been previously published and identified several physiochemical descriptors to be considered in the design of compounds where melanin-binding modulation is desired.