A broad range of agents bind to tubulin and interfere with microtubule assembly, including colchicine binding site inhibitors (CBSIs).
A broad range of agents have been identified to bind to tubulin and interfere with microtubule assembly, including colchicine binding site inhibitors (CBSIs).
They have also facilitated the development of new types of collaborative planning that are characterized by a broad range of agents, new forms of communication, and new roles for planners.
These chemicals are typically toxic to the cell when used alone, but they can also induce resistance to a broad range of agents.
Overexpression of BAG-1 suppresses activation of caspases and apoptosis induced by a very broad range of agents in different cell types (Hohfeld, 1998; Takayama and Reed, 2001), for example chemotherapeutic agents, radiation and growth factor withdrawal.
While such chemicals when used alone are typically toxic to the cell, they can also induce the efflux of a broad range of agents and may therefore prove beneficial to cells in the presence of multiple stressors.
Porcine MRSA ST9 isolates were negative for Panton-Valentine leukocidin genes and resistant to a broader range of antimicrobial agents than that previously described for MRSA ST398 isolated from pigs in the Netherlands (1 ).
It is likely that physiological consequences may be revealed when these mice are exposed to a broader range of infectious agents than are typically present in a barrier facility, or if they are infected with multiple pathogens simultaneously.
Building upon this experience, this paper describes the results for a new microarray design that covers a much broader range of potential biowarfare agents.
Mr. Safina that said chemical pollutants in rivers and industrial areas, an increase in mercury from burning coal and a broader range of bacterial and infectious agents pose additional risks to dolphins.
