Use of multiple AOGCMs [ 83] provides a broader estimate of suitable conditions for L. rufescens, but we acknowledge that ensemble-modeling approaches may shed additional light on model-dependent results (see [ 24]).
An analogous algorithm, Classifier for Olfactory Receptor Pseudogenes (CORP) [ 43], was previously used to identify 30 SNP variations for which one of the alleles is likely inactive [ 26], with a broader estimate of as many as 135 functionally inactive missense alleles in the reference genome [ 43].
To better understand the diversity present in the population, we repeated this analysis, but with a broader estimate of mutation rate (for the prior, the same mean as above, 5.5 x 10-10 mutations/butday, but with a larger standard deviation), resulting in a 5 to 55 fold increase in the estimated substitution rate, and a corresponding reduction in the likely TMRCA (Author response image 2B,C).
Our research broadly chimes with findings by mortgage broker Anderson Harris, which gave us some broad estimates of what they expect could be achieved.
Broad estimates of valley incision have been calculated from previously dated deposits.
But the Parliamentary Commissioner for Standards found the claims also covered travel, subsistence, hospitality and the purchase of books and other publications and were broad estimates of what the MP judged he had spent, rather than receipted items.
These represent general priority areas for REDD+ mitigation, as well as broad estimates of the amount of CO2 that could be saved as a result of successful REDD+ mitigation actions.
We used a comparator vaccine group of 25 to permit broad estimates of the incidence of local and general side effects and of immune responses among vaccine recipients compared to controls.
We acknowledge, however, that these reconstructions are merely broad estimates of potential refugial conditions for L. rufescens and lack constraining data for the earlier half of the epoch.
