Sentence examples for broader defects from inspiring English sources

In addition, we evaluated the occurrence of broader defects of heterochromatin in relation to BRCA1 status in breast cancer cells.

Finally, we evaluated the occurrence of broader defects of heterochromatin in breast cancer cells in relation to BRCA1 status.

Even though D0264, D0067, and D0177 were isolated for defective LTM in an olfactory paradigm, they display distinct behaviors in the optomotor maze, suggesting broader defects in short-term behavioral processes.

To assess whether broader defects on heterochromatin are specifically associated with BRCA1-deficit, we evaluated the features of whole heterochromatin in two breast cancer cell lines with different BRCA1 constitution, MCF7 (BRCandt) and HCC1937 (BRCA1−/−).

A first step should be to separate any direct inhibitory role of the bacterial flora itself, whether in mucus-associated biofilm or in the lumen, from the broader defects that may be consequent on the altered architecture and function of the intestinal mucosa.

Treg deficiency caused by the ablation of PP4 is fairly broad, encompassing defects in nTreg/iTreg differentiation, suppressor functions and gut homeostasis.

All samples only showed fluorescence at wavelengths referable to the specific dye used for the biofunctionalization; a broader defect luminescence was not detected.

Thus, while rsp5 mutant strains exhibit broad defects in the heat-induced endocytic response, Δart1 mutant cells are defective for the turnover of only a subset of PM proteins.

The firms made material misrepresentations about the quality of the loans in the securities, the lawsuit said, and ignored evidence of broad defects among the loans that they pooled and sold to investors.

These mutants show a variety of phenotypes, from broad defects in many sensory modalities to defects in the response to a single odorant [13].

Endocrine progenitor cells lacking Insm1 were less differentiated and exhibited broad defects in hormone production, cell proliferation and cell migration.