As the changes in N chemical shifts that underlie the resonance line-broadening process are primarily dependent on the backbone torsion angles [ 60], the substantially elevated R2 values from Glu to Leu across the entire β4 β5 loop as well as into the β3a strand suggest an appreciable alteration of structure in this region of the protein.
The pope, broadening a process of reconciliation that began in the 1960's during the Second Vatican Council, has issued apologies before, notably regretting in a 1998 document the failure of many Catholics to help Jews during the Holocaust.
But Mr. Köhler added that any agreement with the I.M.F. would necessarily involve "a need to deepen and broaden the process of structural reform".
Instead of rubber-stamping nominees suggested by Congressional leaders, he should broaden the process — with a blue-ribbon search panel, perhaps.
Broadening recruitment processes to include people from the arts and the humanities, exposing business executives to artistic practices, creating emotional experiences that are powerful enough to move people to imagine new possibilities.
Pope John Paul has broadened the process for earning an indulgence (a visit to the Rome airport chapel counts, and so does quitting smoking for a day), but traditionalists will still visit at least one of Rome's four main basilicas.
"This study considerably broadens the processes we think the AIP is involved in," he says.
Interestingly, a recent study demonstrates that LPMOs could also cleave hemicelluloses [ 42], which broaden oxidative processes to non-cellulosic polysaccharides from plants.
Travel may be broadening, but the process isn't instantaneous.
"Previously to work at a place like Vogue you have to have a certain kind of background," he said, adding the magazine had gone from "strength to strength" since broadening its hiring process to target candidates from "inner cities".
