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These results suggested that a 9-h wear time was safe and well tolerated, and provided a broad window of efficacy with once-daily dosing.
Serologic diagnostic techniques provide a broad window of detection relative to direct virus detection, which is limited to the period of active infection/virus replication.
Therefore, there may exist a broader window of opportunity for early detection and prevention of this deadly disease.
High, broad windows at strategic intervals bring in views of the countryside, reinforcing the feeling of old meeting new.
Part of the problem is the broad window, anytime from July to December.
Further larger-scale studies, utilizing a broader range of doses and experimental conditions, are warranted.
Future studies examining a broader range of doses of WIN 55,212-2 would be necessary to definitely determine if a lower dose of this drug might enhance extinction without leading to potential CB1 downregulation.
Chlordecone was tested over the broadest range of doses.
The shape of the curve in Figure 2 indicates that for the purpose of identifying as many relationships as possible, choosing an overly broad window size is preferable to overly constraining a window size a priori.
Although this may be surprising, we believe that this could be an indicator of the broad safety window of rivaroxaban in patients with complex co-morbidities, which would be in contrast to VKA therapy, which has a narrow therapeutic window.
The co-culture of T. versicolor is not highly synchronous, so our sample of haustoria represents a broad temporal window of connections that are ~8-10 days old.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com