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Studies have not been previously conducted on ERGIC3 expression in a broad variety of normal human tissues.
1α,25OHD exerts physiological functions including regulation of growth and differentiation in a broad variety of normal and malignant cells [ 13– 20] including melanoma [ 21].
Furthermore, we systematically investigated expressions of ERGIC3 in a broad variety of normal human tissues and various types of tumors by immunohistochemistry.
In this study, therefore, we looked for relative stable endogenous reference gene challenging a 17,000 cDNA clone data base against approximately 400 specimens that included a broad variety of normal and neoplastic tissues as well as cell lines.
13 In this study, we developed a new murine monoclonal antibody (mAb) against ERGIC3, and systematically investigated ERGIC3 expressions in a broad variety of normal human tissues and various types of human tumors.
There is an urgent need to comprehensively assess epigenetic alterations on a genomic scale in a broad variety of normal cells, stem cells, and in corresponding cancer cells and to assess the importance of the role of small RNAs and their therapeutic potential.
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In contrast, non-linear estimation normally includes a broad variety of statistical procedures.
In addition to normal cells, 5-LO Xis expressed by a broad variety of cancer cells including breast cancer cells [22], [40], [41], [42].
These data suggest that agents that inhibit PQC pathways should be more toxic to cancer cells than normal cells, and might be used to treat a broad variety of cancers.
A broad variety of implantable electrical and chemical recording devices have made innumerable and seminal contributions to our current understanding of normal brain function and the pathology of brain disorders and injuries.
Node age estimates were therefore obtained by Bayesian-calibrated phylogenies using an uncorrelated log-normal relaxed clock as suggested for protein-coding genes in a broad variety of species [ 75].
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