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Rovai, Wighting, Baker, and Grooms (2009), based on the meta analysis of 232 comparative studies performed by Bernard et al. (2004) indicated that there is a broad variability in the results achieved by students on distance (online) learning courses and classroom courses.
Additionally, the broad variability in the severity and spectrum of clinical symptoms in GBS patients suggests that host susceptibility may play a substantial role in disease development [12], [13].
Given that there is broad variability in the severity and spectrum of clinical symptoms in GBS patients [12], [13], host-susceptibility may play a substantial role in the development of GBS [60], [61].
However, because of the individual susceptibility to different inhibitory molecules, the blockade of single inhibitory pathways shows a broad variability in the recovery of T-cell response to persistent viral stimulation, such as defects in CD8+ T cells remain after PD-1 pathway blockade.
Finally, further data that exemplify the broad variability in the A3 locus come from copy number variation studies in humans, with several reports on the loss of the A3A (and/or and/or the A3B A3Z2a-A3Z1bb) genes (Additional file 4: Figure S3).
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The broad variability in these results is probably due to the complexity of the classification, and accord with the results of other studies that evaluated the classification for fractures of other bones [ 17, 26].
It offers the advantage of controlled degree of polymerization and polymer architecture for polymers with low dispersity and broad variability in terms of the chemical functionalization of the polymer side chains through the use of functional monomers.
However, the combination of the limited number of patients in the treatment groups, the broad variability in their growth responses, and the premature stop/reduction of GH dose will underestimate the result of the study regarding changes in IGF-ISDS, IGFBP-3SDS and IGF-I/IGFBP-3 ratioSDS, as well as the dose-dependent effect on pubertal gain in heightSDS.
On the other hand, by making an analysis inside the clinical group, one can perceive a broad variability in every one of the variables, which corroborates the idea of intragroup heterogeneity among migraine sufferers.
However, due to the broad variability in field productivity and the difficulty in predicting material demands by field activities, it is more challenging to achieve efficiency in supply chain management in the construction industry than in the manufacturing industry (Dubois and Gadde 2002; Tommelein et al. 2003).
On the one hand, the different types of evidence exhibit a very broad variability in confidence and on the other hand, the objects itself, e.g. TUs, TFBSs or promoters, have different characteristics and are supported by different types of evidence.
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Justyna Jupowicz-Kozak
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