Sentence examples for broad toxicity from inspiring English sources

"There were many theories as to how castor oil worked, including broad toxicity to intestine cells and effects on water and electrolytes," says Offermanns.

Given that microRNAs do not appear to have any obvious feedback mechanism to report the addition of new target mRNA molecules, it seems unlikely that increasing the quantity of mRNA target, as was done in this study, for a single microRNA will cause such broad toxicity.

The therapeutic goal is to reduce the broad toxicity associated with many of the microtubule chemotherapeutics and direct the treatment at malignant cell hallmarks.

The panel advised that pulmonary is a broad toxicity which encompasses many other toxicities and therefore it would be difficult to evaluate.

These experiments were done for both the EWS-FLI1-high and the EWS-FLI1-low cell state, and they used drug concentrations that were low enough to avoid broad toxicity.

However, such a broad cellular toxicity may also prove to be useful as a therapeutic against various pathogenic and endogenous cellular insults.

Ahn et al. reported an E. coli array consisting of optically coded functional microbeads containing both bioluminescent reporter bacterial cells and fluorescent microspheres for broad-range toxicity monitoring [ 63].

Current primary options for anti-inflammatory management of acute gout (nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and colchicine) bluntly dampen these inflammatory mechanisms in a cost-effective manner, though are limited by broad drug toxicities, particularly in subjects with significant co-morbidities [ 8- 13].

Widespread and persistent organochlorine (OC) contaminants, such as polychlorinated biphenyls (PCBs) and pesticides, are known to have broad-ranging toxicities in wildlife.

Antimicrobial peptides (AMPs) are promising candidates in the fight against antibiotic-resistant pathogens due to their low toxicity, broad range of activity and unspecific mechanism of action.

Those two chemicals offer a broad range of toxicity to insect pests.