Sentence examples for broad target cell from inspiring English sources

Although these toxins have broad target cell specificity, M. haemolytica Lkt is specific for ruminant macrophages, neutrophils and all leukocyte subsets [ 37].

These high-confidence targets illustrate the broad targeting of cell proliferation by miR-203 and suggest mechanisms by which loss of miR-203 can facilitate the expansion of oncogenic Hras-transformed cells.

In this study, we defined the broad range of target cell numbers from several hundred up to 4x10 per testing well.

Thus, the very different dual mechanism we propose for I-BET151's impact on spontaneously developing T1D in NOD mice may reflect several factors, including (but not limited to): pathogenetic differences in induced vs spontaneous autoimmune disease models; our broader analyses of immune target cell populations; and true mechanistic differences between T1D and the other diseases.

Instead, they express various combinations of inhibitory and stimulating receptors to recognize a broad range of target cells [1].

We show that in Stat1-S727A miceNK micellsK cells display higher cytotoxicity toward a broad panel of target cells, leading to more efficient tumor clearance.

Neurons and vascular SMCs and ECs also express FcεR1 (Andoh & Kuraishi, 2004; Wang et al, 2011), suggesting a broad spectrum of target cells for IgE.

Platelet-derived growth factor (PDGF -BB is a homodimeric growth factor with a broad range of target cells, notably mesoderm-derived cells, such as PDGF -BBs and mesangisl cells, but also ectoderm-derived glial cells and neurons.

The induced T cell responses are broad, target multiple epitopes and are predominantly CD4+.

Importantly, IKDCs have a more potent anti-tumor effect than NK cells, and have a broader range of target cells and prevent tumor outgrowth more effectively [ 15].

At the level of the target cell, NSV triggered multiple PRRs in microglia to produce a broad range of inflammatory mediators via non-overlapping signalling pathways.