Sentence examples for broad subtypes of from inspiring English sources
Genentech (which created Herceptin) now imagines what it calls "cancer vaccines," tailored not just to broad subtypes of people but to the unique signature of a person's tumor.
We hypothesized that race/ethnic group, sex, age, and/or calendar period variation in adult glioma incidence differs between the two broad subtypes of glioblastoma (GBM) and non-GBM.
Indeed, chromosomal aberrations allow identifying two broad subtypes of disease, one characterized by chromosomal gains (hyperdiploidy) and the other by structural changes (nonhyperdiploidy), leading to different results in terms of prognosis [ 9].
MM is characterized by significant molecular heterogeneity and comprises two broad subtypes of disease that may reflect different underlying oncogenetic pathways of evolution one characterized by chromosomal gains (hyperdiploidy) and the other by structural changes (nonhyperdiploidy), most commonly involving translocations of the IGH gene, located at 14q32.
Our results suggest that AF may be a viable therapeutic option for broader subtypes of breast cancers.
While AF could have therapeutic effects on broader subtypes of breast cancer, the mechanism of cytotoxicity is complex, and likely, cell line- and tumor-specific.
Breast cancer cell lines have been classified into three broad subtypes based on the expression of the intrinsic genes: luminal, basal A or basal B [ 29, 30].
Three broad clinical subtypes of Gaucher disease are recognized (Balwani et al., 2010).
Primary GBM, which constitute 90-95% of GBM [ 9], differ from non-GBM with respect to DNA copy number [ 11], gene expression [ 11], DNA methylation [ 12- 14], and isocitrate dehydrogenase (IDH) 1 or 2 gene mutation status [ 11- 16], providing a molecular rationale for the two broad glioma subtypes of GBM and non-GBM.
For a broad application range, detection of influenza A virus strains covering a broad subtype spectrum is desirable.
It has been observed that individuals who have recovered from influenza infections develop broad subtype-specific immunity that can protect them from subsequent infection by closely related drift variants of the same subtype [10], [11], [12].
