Sentence examples for broad substrate specificity of from inspiring English sources

A possible explanation for a low number of reactions is the use of a single generic reaction to model the broad substrate specificity of an enzyme instead of explicitly describing each specific reaction separately with the same EC number.

The transgenic plants also showed moderate tolerance and accumulation of arsenic (As) upon exogenous As stress, signifying broad substrate specificity of OsMTP1.

Analysis of the structure explains the broad substrate specificity of the enzyme, and provides the basis for rational design of novel prodrugs and for site-directed mutagenesis for improved enzyme activity.

Substrate specificity of two homoisocitrate dehydrogenases derived from Deinococcus radiodurans and Saccharomyces cerevisiae was analyzed using a series of synthetic substrate analogs, which indicated a relatively broad substrate specificity of these enzymes.

These structures formed the basis for molecular dynamics simulations to understand the broad substrate specificity of this enzyme and the role of active site residues in the phospho-transfer mechanism and oligomerization.

Comparison of the PDZ1 LPA2 structure to the structure of PDZ1 in complex with a different peptide provides insights into the diverse nature of PDZ1 substrate recognition and suggests that the conformational flexibility in the ligand binding pocket is involved in determining the broad substrate specificity of PDZ1.

The current analysis also further highlights that GOOX enzymes characterized to date are not specific to glucose-based substrates, and instead show broad substrate specificity on a number of oligosaccharides including cello- and xylo-oligosaccharides, as well as substituted and branched xylo-oligosaccharides.

However, due to the broad substrate specificities of the lysosomal cathepsins, the specific detection of cathepsin S is difficult when other cathepsins are present.

The broad substrate specificities of the PhaJ4 and PhaC1 STQK) enzymes allowed for the production of homopolymers with strict control over the repeating unit composition from substrates of four to twelve carbons in length.

A broad substrate specificities of azoreductases were reported from alkaliphilic Bacillus badius, Aquiflexum sp., and neutrophilic Lysinibacillus sphaericus against a range of azo dyes and nitro compounds (Misal et al. 2011, 2013, 2014, 2015).

The idea is supported by similar broad substrate specificities of both systems.