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Both TDC1 and TDC 3 are induced by a broad spectrum of pathogens.
Several herbal products have immunostimulant properties, and are environmental friendly, economical and can act against a broad spectrum of pathogens.
The advantages of combination therapy include coverage of a broad spectrum of pathogens and, theoretically, synergistic activity with a decrease in the emergence of resistant strains.
Tea tree oil is known to possess antibiotic activity toward a broad spectrum of pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and Candida albicans [3].
This result indicates that OsHsp18.0-CI belongs to the DR genes, which respond to a broad spectrum of pathogens in rice.
Interferon (IFN) is one of the major regulators of innate immunity, it also mediates the adaptive immune responses to a broad spectrum of pathogens.
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This process requires the production and secretion of a broad spectrum of pathogen enzymes that target and degrade the many complex polysaccharides in the plant cell wall.
Tier B is well suited to agents with a reasonably broad spectrum of pathogen coverage and provides for registration based on a single phase III trial plus small pathogen-focused studies.
The persistence of highly divergent alleles over time may be explained by the hypothesis that increased diversity confers a fitness advantage to the host with an ability to recognize a broader spectrum of pathogens [ 30].
Consistent with this hypothesis, growth inhibition assays showed that B. azoricus gill tissue homogenates inhibit the growth of a broader spectrum of pathogens compared to the symbiont-free foot tissues (Bettencourt et al., 2007).
Crosstalk between the two IFN systems has been proposed as an evolved mechanism to help defend against a broader spectrum of pathogens [ 17], however the complexities of this signalling relationship remain poorly characterized.
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