Sentence examples for broad spectrum of agents from inspiring English sources
The truth is that there is a broad spectrum of agents in the game, but in a general sense they are there to either look after the interests of a player, or to act for a buying or selling club to broker a deal.
Induction of inducible heme oxygenase-1 (HO-1) by a broad spectrum of agents represents an important cytoprotective pathway to alleviate endothelial dysfunction in response to inflammatory insults.
Hypomorphic alleles of the Smc5/6 complex exhibit defects in the repair of DNA damage caused by a broad spectrum of agents, including IR, UV, MMS, mitomycin C and HU [ 5, 69, 73- 76].
The availability of a broader spectrum of agents with different targeting mechanisms will provide more effective treatment options for diverse patient populations.
Previously, we have reported remarkable effect of a quercetin-glutamic acid conjugate to reverse multidrug resistance (MDR) of cancer cells to a broad spectrum of anticancer agents through inhibition of P-glycoprotein (Pgp -mediated drug efflux.
Moreover, 1,25(OH)2D leads to enhanced expression of human cathelicidin, which is an endogenous antimicrobial peptide active against a broad spectrum of infectious agents [33].
Indeed over-expression of the ATP binding cassette transporters such as ABCB1 (MDR1) has been directly implicated in resistance to a broad spectrum of chemotherapeutic agents in vitro including paclitaxel and in some studies carboplatin [24], [25].
Overexpression of the ATP binding cassette transporters such as ABCB1 (MDR1) has been directly implicated in resistance to a broad spectrum of chemotherapeutic agents in vitro including anthracyclines, paclitaxel, and the Vinca alkaloids [25], [26], [27].
Overexpression of P-gp by tumours results in resistance to a broad spectrum of chemotherapeutic agents.
A broad spectrum of infectious agents and their chronic outcomes compose this evolving field.
Moreover, 1,25(OH)2D leads to enhanced expression of human cathelicidin, which is an endogenous antimicrobial peptide active against a broad spectrum of infectious agents [ 33].
