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However, we observed broad specificity of serum IgG responses in both male and female badgers in immunoblots of T. pestanai lysates.
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Taken together with the data above, this suggests that CR growth in vivo is Src dependent whereas the serum-induced in vitro proliferation of CWR22Rv1 or CWR22PC is either Src independent or the broad specificity of dasatinib negates inhibitory pathways required downstream of Src for proliferation in vitro.
However, the mechanisms that support the broad specificity of DcR3 remain to be fully defined.
We also provide molecular evidence for the plasticity of the TAS2R16 binding site and an explanation for the relatively broad specificity of the receptor.
This is similar to the apparent broad specificity of ERAD E3s in targeting different proteins in the ER for degradation.
This may also support the broad specificity of the enzyme.
The specificity of serum protection is linked to the oncornavirus associated with the AD755a tumor and the serum immunoprecipitates only virus structural proteins from the tumor cell surface.
We confirmed the specificity of serum Ma2 autoantibodies by using western blot and sequential immunoprecipitation analyses.
No evidence of organ specificity of serum CEA was found.
Jani, M. et al. Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics.
Primers were designed for the broad specificity detection of both viruses.
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